Cancer Chemotherapy Drugs Some cancer chemotherapy drugs’ mode of action depends on the production of free radicals to destroy tumors.
Queen of Fruit 9-10x Fresh for Life MANGOSTEEN $199.95 $131.78 PURCHASE HERE:http://www.themoringaqueen.com/shop/9-10-fresh-mangosteen/The Fruit for Life MANGOSTEENMangosteen juice and the wonders of a mangosteen whole fruit puree. SCIENTIFIC STUDIES ON MANGOSTEEN
Scientific studies on mangosteen can be found at the U.S. National Library of Medicine, National Institutes of Health (NIH).
Due to international guidelines and company regulations, the publication of this data cannot be shown any longer on this post.
This video podcast below is allowable and has an interesting viewpoint on why Mangosteen continues to be investigated by research institutes from all over the world.Benefits of Mangosteen Juice
MANGOSTEENimages Did you know that mangosteen was the original fruit termed a "Superfruit" in 2004? Neither did I, this recording is full of useful information.Many superfruits are no longer examined by scientists but mangosteen is still under study because of its positive effects on so many people. In universities of 20 countries mangosteen is found on PubMed for 500 plus publications. Commercial companies are trying to turn mangosteen into a drug for at least 3 medical categories. My own personal opinion is get mangosteen in as an original form as possible.
There is an extensive compilation of scientific data on xanthones and mangosteen.
At the center of attention about mangosteen are the biologically active compounds found in the skin of the fruit, called xanthones. Within the last 7 years, the xanthones have been the focus of much scientific research. With over 200 xanthones identified in nature, so far 43 xanthones are identified in the mangosteen fruit. The mangosteen is simply the most singular, abundant source of xanthones on earth. Continued study is required as only 6 of the 43 xanthones found in the mangosteen fruit, have been researched. However, their potent activity and broad-ranging indications for use may soon reveal the mangosteen’s xanthones to be one of the all-time greatest medical discoveries.
Diagram of xanthone with mangosteen fruit
THESE ABSTRACTS WILL NOT INCLUDE OTHER BIOLOGICALLY ACTIVE COMPOUNDS IN MANGOSTEEN.
Unique for its appearance and flavor, mangosteen is often revered as queen of the tropical fruits, especially in the oriental regions. This exotic, purple color fruit is quite popular for its snow-white, juicy, delicious arils all over the Asian countries, and in recent years by the European and American fruit lovers as well!
Botanically, it is the fruit belonging to the family of Clusiaceae, in the genus: Garcinia. Scientific name: Garcinia mangostana.Mangosteen nutrition facts:
mangosteen fruit mangosteensPurple mangosteen.(Garcinia Mangostana).Note deep purple colorfruit with light green calyx. God Superfoods Store
Mangosteen plant is an evergreen, erect tree reaching about 20- 60 ft in height. It commonly found in tropical rainforests of Indonesia, Malaysia, Thailand and Philippines as well as in some cultivated orchards in Sri Lanka, and India, where annual precipitation and relative humidity are favorable for its growth. Fresh purple fruits are available in the markets from June until October.
Each tree bears several deep purple colored round shaped fruits, capped with light green calyx at the stem end. Completely matured fruit measures about 3-7 cm in diameter. Its outer tough rind is about 7-12 mm thick, contains bitter yellow latex that stains clothes black.
Internally; the fruit features 4 to 10 juicy, snow-white color, soft, fleshy, triangular segments as in oranges. Each segment may contain 1-4 off-white colored seeds. Seeds are inedible and bitter in taste. The flavor of the fruit can be described as sweet, fragrant, and delicious.lemon-drop mangosteens and african mangosteensLemon-drop, and African mangosteens (Imbe). The fruits are smaller than purple ones.
Different species of Garcinia genus are grown all around the Southeast Asia, Africa, and South America all along the tropical belt. Cherapu or Button mangosteen (Garcinia prainiana) is native to Malaysia. It features somewhat flat, mandarin orange-like shape with thin rind that can be peeled very easily by hand, again as in oranges.
Lemon drop mangosteens (Garcinia madruno) are small size (2-4 cm diameter) fruits, native to Malayan peninsula. African mangosteen or Imbe (Garcinia livingstonei) is native to West Africa. They are slightly larger than lemon drop type.
Health benefits of mangosteen
Delicious and juicy, mangosteen is one of the popular tropical fruits. It comprises an impressive list of essential nutrients, which are required for normal growth and development and overall nutritional well-being. This fruit is very low in calories (63 calories per 100 g) and contains no saturated fats or cholesterol. Nonetheless, it is rich in dietary fiber (100 g provides about 13% of RDA), which can be very important for individuals who are concerned about putting on excess body weight. Mangosteen is good in vitamin C and provides about 12% of RDA per 100 g. Vitamin-C is a powerful water soluble anti-oxidant. Consumption of fruits rich in vitamin C helps the body develop resistance against flu-like infectious agents and scavenge harmful, pro-inflammatory free radicals. Fresh fruit is a moderate source of B-complex vitamins such as thiamin, niacin and folates. These vitamins are acting as cofactors the help body metabolize carbohydrates, protein, and fats. Further, it also contains a very good amount of minerals like copper, manganese and magnesium. Potassium is an important component of cell and body fluids and helps control heart rate, and blood pressure; thus, it offers protection against stroke and coronary heart diseases.
See the table below for in depth analysis of nutrients:Mangosteen (Garcinia mangostana), Fresh,Nutrition value per 100 g(Source: USDA National Nutrient data base)Principle Nutrient Value Percentage of RDAEnergy 63 Kcal 3%Carbohydrates 15.6 g 12%Protein 0.50 g 1%Total Fat 0.4 g 2%Cholesterol 0 mg 0%Dietary Fiber 5.10 g 13%Vitamins Folates 31 µg 8%Niacin 0.286 mg 2%Pantothenic acid 0.032 mg <1%Pyridoxine 0.041 mg 3%Riboflavin 0.054 mg 4%Thiamin 0.054 mg 4.5%Vitamin A 35 IU 1%Vitamin C 7.2 mg 12%Electrolytes Sodium 7 mg 0.5%Potassium 48 mg 1%Minerals Calcium 5.49 mg 0.5%Copper 0.069 mg 7%Iron 0.17 mg 2%Magnesium 13.9 mg 3.5%Manganese 0.10 mg 4%Phosphorus 9.21 mg 1%Zinc 0.12 mg 1%Phyto-nutrients Carotene-α 1 µg –Carotene-ß 16 µg –Cryptoxanthin-ß 9 µg –Selection and Storage
Mangosteens are available fresh during summer months. Completely matured, deep purple color fruits are picked up either by hand or hook-and-basket method as in mangoes, without damaging them. Injury to outer skin results in percolation of bitter-latex into the edible flesh, which makes the whole fruit bitter and inedible.
Mangosteen is now readily available in the supermarkets across the United States. While buying, look for fresh fruits that feel heavy in hand with firm green calyx at the stem end, and bright purple color skin as they indicate fresh arrivals from East Asian orchards. Avoid those appearing dry and blotched skins as they may indicate an old stock.
At home, ripe fruits should be placed in cool well-ventilated place where they keep well for up to two weeks. For extended keeping quality store them inside the refrigerator.
Preparation and Serving tips
Wash fruit in water to remove surface dust. Fresh fruit has a thick soft rind, quite like in pomegranate but thicker in size. In general, the fruit is scored through the rind around an equatorial circumferential fashion using paring knife, and its upper half pulled up gently using the thumb to expose delicious arils inside.
Prolonged exposure to hot conditions may cause its outer skin dry, brittle and may pose problems while peeling.mangosteen cut section showing arilsInside of the mangosteen. Note for the snow-white segments (arils).
Here are some serving tips:
Fresh mangosteens are wonderfully delicious. Enjoy this exotic juicy fruit all alone without any additions.
The fruit segments complement well with other fruit sections like papaya, watermelon, pineapple, grapes, etc.
Mangosteen juice is very tasty thirst quenching cool drink to beat summer heat.
Mangosteen clafouti prepared using corn flour and coconut milk is a delicious dessert.
History of the Mangosteen
The Mangosteen, or Garcinia mangostana, was named for Dr. Laurentiers Garcin, a French doctor, priest and explorer, who was the first to scientifically study the Mangosteen. He noted its long-standing use in traditional Asian medicines, as reference to such use was found in records dating back to the Ming Dynasty in China.
The Mangosteen is the national fruit of Thailand, and is common throughout Southeast Asia. Legend holds that Queen Victoria of England so loved the Mangosteen that she offered varying rewards — from money to knighthood — to anyone who could bring her a Mangosteen in pristine ripeness.
Growing the Mangosteen
The Mangosteen is a very slow-growing fruit tree. Young trees do not produce fruit generally until 10 years of age. The prime harvest period for most Mangosteen trees is between 20 and 45 years old, with many trees still producing fruit after 100 years. Mangosteen trees can grow to be as tall as 75 feet, and harvesting must be done by hand, as the result of a hard fall can severely damage the fruit.
Mangosteen trees need humid, tropical environments to thrive and produce fruit. Because of the specific environmental requirements, cultivation of the Mangosteen has been largely confined to plantations in its native habitats of Thailand, Malaysia, Indonesia and the Philippines. Expansion of Mangosteen cultivation has been attempted in Sri Lanka, South India, Central and South America, Australia, Brazil, and Florida and Hawaii in the United States, all with mixed results and only small harvests where the cultivation has been successful.
How to Eat a Mangosteen
Fresh Mangosteen is best opened using only your hands. Within the first few days of harvesting, the purple rind of the fruit remains soft, and the fruit inside can be exposed with a gentle squeeze and twist of the rind. If possible, avoid using a knife to prevent damage to the fruit segments inside.
Outside of major cultivation areas, Mangosteen fruit are likely to be several days away from ripeness. At that point, the outer rind will be hard you will have to use a knife. Run the knife at a shallow level around the rind of the fruit, parallel to the stem. The rind is very bitter and the stains from the rind are difficult to remove, so be careful not only to avoid spilling the juice from the rind onto stainable services (including skin) but also to avoid mixing bits of the rind with the inner fruit.
Once opened, the edible inner segments will be seen. Generally, one segment will contain the seed(s), so take care when eating the individual segments.
Scientists also are conducting trials with Mangosteen peel as potential HIV drug for future treatments.
Here are most common health benefits of Mangosteen skin properties:
Anti-fatigue (energy booster / energize)
Powerful anti-inflammatory (prevents inflammation / anti-inflammatory)
Analgesic (prevents pain / prevent nerve pain)?
Anti-ulcer (stomach, mouth and bowel ulcers)
Anti-depressant (low to moderate / preventing depression)
Anxyolytic (anti-anxiety effect / prevent anxiety, panic & anxiety)
Anti-Alzheimerian (helps Prevent dementia / prevent penyegah Alzheimeria)
Anti-tumor and cancer prevention (shown to be capable of killing cancer cells / Prevent cancer)
Immunomodulator (helps the immune system / immune system)
Anti-aging (anti aging)
Anti-oxidant (Remove toxic / poison in the body)
Anti-viral (kills germs)
Anti-biotic (modulates bacterial infections)
Anti-fungal (prevents fungal infections / fungal infections)
Anti-seborrheaic (prevents skin disorders / skin mencantikkan)
Anti-lipidemic (blood fat lowering / remove cholesterol)
Anti-atherosclerotic (prevents hardening of arteries)
Cardioprotective (Protects the heart / to the heart)
Hypotensive (lowering blood pressure / blood pressure lowering)
Hypoglycemic (anti-diabetic effect, helps lower blood sugar / reduced sugar in the blood)
Anti-obesity (helps with weight loss / gain kuruskan)
Anti-arthritic (prevention of arthritis / prevent bone pain)
Anti-osteoporosis (helps prevent the loss of bone mass / brittle bones)
Anti-periodontic (prevents gum disease / prevent bleeding gums)
Anti-allergenic (prevents allergic reaction)
Anti-calculitic (prevents kidney stones / rocks prevented)
Anti-pyretic (fever lowering / lowered body temperature)
Anti-Parkinson (Parkinson neurological diseases)
Anti-diarrheal (preventing diarrhea)
Anti-neuralgic (reduces nerve pain / nerve pain)
Anti-vertigo (prevents dizziness)
Anti-glaucomic (prevents glaucoma / eye pain)
Anti-cataract (prevents cataracts)
Pansystemic (has a synergistic effect on the whole body / Offsetting the whole body)
Maintains optimal thyroid function
Side Effects of Mangosteen
Mangosteen may cause some side effects in hyper-sensitive individuals, including those who have allergies to fruits.
Additionally, some Mangosteen products in the market include extracts from other fruits that also may cause allergic reactions or side effects.
Allergic reactions like headaches, itchy skin rashes and minor or transient joint pains are possible. The reported allergic reactions from Mangosteen, though, do not involve respiratory problems or life-threatening situations.
Loose Stools or Constipation
Those who begin their supplementation with servings of more than one ounce of Mangosteen supplement may experience temporary loose stools.
Also, in the constipation-predominant type of Irritable Bowel Syndrome (IBS), and in diabetic patients diagnosed with gastroparesis complication, more than one ounce a day may worsen the constipation.
In these instances, reducing the servings will likely solve the problem.
Polycythemia Rubra Vera
Mangosteen can increase red cell mass and therefore should not be used by people diagnosed with polycythemia rubra vera.
Some fruits and foods are known to affect the mode of action and efficacy of certain drugs.
For example, large quantities of grapefruit juice can affect the blood levels of some drugs (e.g., lipid-lowering drugs) and may alter these drugs’ effects in the body.
Also, certain foods can either speed up or slow down the liver’s drug-detoxification activity when these foods also affect the elements of the P450 enzyme system involved in the drug-detoxification process. There is no precise information yet on how the Mangosteen may affect the P450 enzyme system.
As of this writing, there has not been any reported adverse food-drug interactions with the Mangosteen despite its use by thousands of people using a wide variety of commonly prescribed drugs.
Although this is not to be taken to mean that food-drug interactions do not exist, a level of confidence continues to be established as far as the fruit is concerned.
Foods that contain vitamin K can affect Coumadin blood levels. In his book, “Mangosteen: The X-Factor”*, Dr. J. Frederic Templeman suggests that Coumadin users drink the juice “at the dose they intend to consume daily and, after 3 days of use at this level, to go into the doctor’s office to have a finger-prick check of the Coumadin’s effect.”
He says that many consumers on Coumadin use the Mangosteen supplement safely, and that he has “not received a documented report of Coumadin problems where the supplement appeared to be the culprit.”
Cancer Chemotherapy Drugs
Some cancer chemotherapy drugs’ mode of action depends on the production of free radicals to destroy tumors. Because Mangosteen contains powerful antioxidants that fight free radicals, it would be wise to ask the pharmacist or consult the Physician’s Desk Reference on the Internet on the mode of action of any particular cancer chemotherapy drug.
If the mode of action of a chemotherapy drug has nothing to do with the production of free radicals, such that Mangosteen’s powerful antioxidants will not interfere with the drug’s mode of action, then it may be wise to consider the highly beneficial effects the fruit can provide cancer chemotherapy patients.
Several studies proved that high regular doses of antioxidants, such as those available from the Mangosteen, clearly suppressed cancerous cell growth.
Summary of Mangosteen Side Effects
So who should take some precautions because of some potential Mangosteen side effects or allergic reactions?
Individuals with allergies to fruits, polycythemia rubra vera patients, Coumadin users, or cancer patients taking chemotherapy drugs whose efficacy relies on the production of free radicals, are some of the known caveats.
Please consult with your Physician before trying this fruit as a treatment for of the above mentioned. Also keep in mind that if purchasing products that claim to contain the Mangosteen fruit, please be sure to verify if these statements have been evaluated by the FDA.
We are not Physician and therefore do not claim that this fruit will treat, cure or prevent any disease. This article is for informative purposes only.